What special precautions should I follow?   

Stop  taking this drug at  the first sign  of drug allergy or sensitivity. People have died from abacavir sensitivity. People with liver disease should be cautious about using this drug because of  the possibility that it can aggravate  the condition. Some people  have died from liver damage associated with abacavir. The use of nucleoside drugs such as abacavir can very rarely cause lactic acidosis, a fatal metabolic disturbance. Resistance  to abacavir has developed in laboratort versions of HIV also resistant to lamivudine, didanosine and zalcitabine. HIV that is resistant to protease inhibitors is  not likely to be resistant to  abacavir. Redistribution or accumulation  of body fat may occur in people  taking antiviral medications including: central obesity; facial arm, leg, and/ or buttock wasting; breast enlargement; and fat accumulation at  the base of  the neck (buffalo hump). Abacavir cannot be used in infants under age 3 months.