What side effects can this medication cause?

Alefacept may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• dizziness
• muscle pain
• pain, redness, swelling, or bleeding in the place where alefacept was injected

Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:

• hives
• rash
• itching
• swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
• difficulty breathing or swallowing
• hoarseness
• fever, sore throat, chills, and other signs of infection
• cough
• changes in skin such as new or changed sores, spots, lumps or moles
• lumps or masses in any part of the body
• upset stomach
• vomiting
• loss of appetite
• extreme tiredness
• stomach pain
• yellowing of the skin or eyes
• easy bruising
• dark urine
• pale stools

Alefacept may increase the risk that you will develop cancer. Talk to your doctor about the risks of using this medication.

Alefacept may cause other side effects. Call your doctor if you have any unusual problems while using this medication.

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online at http://www.fda.gov/MedWatch/report.htm or by phone 1-800-332-1088.