What special precautions should I follow?

Before taking almotriptan:

• Tell  your doctor and pharmacist if you are allergic to almotriptan or any other medications.
• Do  not take almotriptan within 24 hours of another selective serotonin receptor agonist such as eletriptan (Relpax), frovatriptan (Frova), naratriptan (Amerge), rizatriptan (Maxalt), sumatriptan (Imitrex), or zolmitriptan (Zomig); or ergot-type medications such as bromocriptine (Parlodel), cabergoline (Dostinex), dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylates (Germinal, Hydergine), ergonovine (Ergotrate), ergotamine (Bellergal-S, Cafergot, Ergomar, Wigraine), methylergonovine (Methergine), methysergide (Sansert), and pergolide (Permax).
• Tell  your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking, have recently stopped taking, or plan to take. Be sure to mention any of the following: antifungals such as fluconazole (Diflucan), itraconazole (Sporanox), and ketoconazole (Nizoral); cimetidine (Tagamet); clarithromycin (Biaxin); cyclosporine (Neoral, Sandimmune); danazol (Danocrine); delavirdine (Rescriptor); diltiazem (Cardizem, Dilacor, Tiazac); erythromycin (E.E.S., E-Mycin, Erythrocin); HIV protease inhibitors such as indinavir (Crixivan) and ritonavir (Norvir); isoniazid (INH, Nydrazid); metronidazole (Flagyl); nefazodone (Serzone); selective serotonin reuptake inhibitors (SSRIs) such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, in Symbyax), fluvoxamine, paroxetine (Paxil), and sertraline (Zoloft); selective serotonin/norepinephrine reuptake inhibitors (SNRIs) such as duloxetine (Cymbalta) and venlafaxine (Effexor); troleandomycin (TAO); and zafirlukast (Accolate). Also tell your doctor or pharmacist if you are taking the following medications or if you have stopped taking them within the past two weeks: monoamine oxidase (MAO) inhibitors, including isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl), and tranylcypromine (Parnate). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
• Tell  your doctor if you smoke, if you or any family members have or have ever had heart disease, if you have gone through menopause (change of life), and if you have or have ever had a heart attack; angina (chest pain); high blood pressure; high cholesterol; diabetes; circulation problems; or kidney or liver disease.
• Tell  your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking almotriptan, call your doctor.
• You  should know that almotriptan may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
• Talk  to your doctor about your headache symptoms to make sure they are caused by migraine. Almotriptan should not be used to treat hemiplegic or basilar migraine or headaches caused by other conditions (such as cluster headaches).

What special dietary instructions should I follow?  

Talk to your doctor about drinking grapefruit juice while taking this medicine.