Amobarbital and Secobarbital
What are other names for this medicine?
Type of medicine: barbiturate
Generic and brand names: secobarbital and amobarbital, oral; Tuinal 100-Mg Pulvules; Tuinal 200-Mg Pulvules
What is this medicine used for?
This medicine is used to relieve tension or anxiety, to help you sleep, or to prevent seizures. It may be used for other conditions as determined by your health care provider.
What should my health care provider know before I take this medicine?
Before taking this medicine, tell your health care provider if you have ever had:
- an allergic reaction to any medicine
- depression or thoughts of suicide
- liver or kidney disease
- lung disease
- porphyria (chemical imbalance that can affect the nerves and skin)
- problems with substance abuse.
Females of childbearing age: Tell your health care provider if you are pregnant or become pregnant while taking this medicine. This medicine is not usually taken during pregnancy because it may harm the baby. However, your seizures need to be controlled. This medicine may make birth control pills less effective. If you need birth control, talk to your health care provider about methods that are effective while you are taking this medicine. Do not breast-feed while you are taking this medicine.
How do I use it?
Take this medicine exactly as your health care provider prescribes. Do not take more of it or take it longer than prescribed. Taking too much may be habit-forming or you may overdose.
For this medicine to prevent seizures, you must take it regularly. If you are taking this medicine to help you sleep, take it 30 to 60 minutes before bedtime.
If you miss a dose, take it as soon as you remember, unless it is almost time for the next dose. In that case, skip the missed dose and take the next one as directed. Do not take double doses. If you are not sure of what to do if you miss a dose, or if you miss more than one dose, contact your health care provider.
What should I watch out for?
Do not stop taking this medicine without your health care provider's approval, especially if you have taken it for more than 2 weeks. You may have to reduce your dosage gradually to prevent serious side effects.
This medicine will make you drowsy. Do not drive or operate machinery until you are fully alert.
This medicine may increase the effects of alcohol and other drugs that slow down your nervous system. Do not drink alcohol or take other medicines unless your health care provider approves.
This medicine may make your skin more sensitive to the sun, which may lead to painful sunburns. While you are taking this medicine, avoid long exposure to the sun. Wear protective clothing, a hat, and sunscreen lotion when you need to be outdoors. Do not use a sunlamp. If you get a severe sunburn, contact your health care provider right away.
The signs of overdose are severe drowsiness, trouble breathing, or acting like you are drunk. If you think you have taken an overdose, get emergency medical treatment right away.
This medicine may produce excitement rather than calming in some people. If this happens, contact your health care provider.
This medicine is a controlled substance. It is illegal to give this medicine to anyone else.
Adults over the age of 65 may be at greater risk for side effects. Talk with your health care provider about this.
What are the possible side effects?
Along with its needed effects, your medicine may cause some unwanted side effects. Some side effects may be very serious. Some side effects may go away as your body adjusts to the medicine. Tell your health care provider if you have any side effects that continue or get worse.
Life-threatening (Report these to your health care provider right away. If you cannot reach your health care provider right away, get emergency medical care. Allergic reaction (hives; itching; rash; trouble breathing; tightness in your chest; swelling of your lips, tongue, and throat).
Serious (report these to your health care provider right away): Muscle or joint pain, sore throat, nosebleeds, yellow skin or eyes, sensitivity to the sun, fever, hallucinations (seeing or hearing things that are not there), severe depression, confusion.
Other: Dizziness, drowsiness, headache, nervousness, nightmares, stomach upset, vomiting.
What products might interact with this medicine?
When you take this medicine with other medicines, it can change the way this or any of the other medicines work. Nonprescription medicines, vitamins, natural remedies, and certain foods may also interact. Using these products together might cause harmful side effects. Talk to your health care provider if you are taking:
- acetaminophen (Tylenol)
- alcohol
- antianxiety medicines such as clonazepam (Klonopin), alprazolam (Xanax), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), oxazepam (Serax), triazolam (Halcion), temazepam (Restoril), and flurazepam (Dalmane)
- antibiotics such as rifampin (Rifadin, Rimactane), chloramphenicol (Chloromycetin), doxycycline (Vibramycin, Doryx, Vibra-Tabs), and rifabutin (Mycobutin)
- antihistamines such as diphenhydramine (Benadryl) and chlorpheniramine (Chlor-Trimeton)
- antiseizure medicines such as carbamazepine (Tegretol), phenytoin (Dilantin), and valproic acid (Depakote, Depakene)
- beta blockers such as atenolol (Tenormin), acebutolol (Sectral), pindolol (Visken), metoprolol (Lopressor, Toprol XL), sotalol (Betapace), nadolol (Corgard), propranolol (Inderal), labetalol (Normodyne, Trandate), and carvedilol (Coreg)
- calcium channel blockers such as amlodipine (Norvasc), nifedipine (Adalat, Procardia), isradipine (DynaCirc), felodipine (Plendil), verapamil (Calan, Isoptin), diltiazem (Cardizem), and nicardipine (Cardene)
- birth control pills and hormones such as estradiol (Estrace, Estratab), conjugated estrogens (Premarin), norethindrone (Aygestin, Micronor), and norgestrel (Ovrette)
- blood thinners such as warfarin (Coumadin)
- corticosteroids such as cortisone (Cortone), betamethasone (Celestone), dexamethasone (Decadron), hydrocortisone (Cortef, Hydrocortone, A-HydroCort), prednisone (Meticorten, Deltasone), prednisolone (Delta-Cortef, Prelone), methylprednisolone (Medrol, A-Methapred), and triamcinolone (Aristocort, Kenacort)
- griseofulvin (Fulvicin U/F, Grifulvin V, Grisactin)
- immunosuppressants such as azathioprine (Imuran), cyclosporine (Sandimmune, Neoral), mycophenolate mofetil (Cellcept), sirolimus (Rapamune), and tacrolimus (Prograf, Protopic)
- MAO inhibitor antidepressants such as phenelzine (Nardil), tranylcypromine (Parnate), and isocarboxazid (Marplan) (Do not take this medicine and an MAO inhibitor within 14 days of each other.)
- medicines to help you sleep such as zolpidem (Ambien) and zaleplon (Sonata)
- mephenytoin (Mesantoin) and ethotoin (Peganone)
- metronidazole (Flagyl)
- muscle relaxants such as tizanidine (Zanaflex), cyclobenzaprine (Flexeril), carisoprodol (Soma), methocarbamol (Robaxin), dantrolene Dantrium), and baclofen (Lioresal)
- theophylline (Theobid)
- tretinoin (Vesanoid).
Keep a list of all your medicines (prescription, nonprescription, supplements, natural remedies, and vitamins) with you. Be sure that you tell all health care providers who treat you about all the products you are taking.
How should I store this medicine?
Store this medicine at room temperature. Keep the container tightly closed. Protect it from heat, high humidity, and bright light.