Amphotericin B (Injection)

Amphotericin B

Treats infections caused by a fungus. Belongs to a class of drugs called antifungals. 

Brand Name(s):  NovaPlus Amphotericin B

There may  be other brand names  for this medicine. 

When This Medicine Should Not Be Used: 

You should not use this medicine if you have ever had an allergic reaction to amphotericin B. 

How to Use This Medicine: 

Injectable

• Your doctor will prescribe  your exact dose and tell you how often it should  be given. Keep all medicine out of the reach of children. 
• An IV infusion is medicine  that is put directly into  your body through one of your veins.
• This medicine should be given by a person trained to give an IV, such as a nurse. Sometimes you, a family member,  or friend can be taught  to give  your medicine. 
• Check  the bag  to make sure there are no leaks. Also make sure  the solution is clear. 

If a dose is missed: 

• This medicine needs to be given on a regular schedule. Take the missed dose as soon as you remember. 
• If you miss more than one dose, call your doctor for instructions. 

How  to Store  and Dispose of This Medicine: 

• Store  in a refrigerator. Do  not freeze. Take it  out of the refrigerator an hour before the time for your next dose  and allow it  to warm  to room temperature in a clean, dry place. 
• If you see particles in  the solution, You should  not use it. 
• If you have  your treatments at home,  you should be given a special container for  the used needles. Keep it  where children  or pets cannot reach it. 

Drugs and Foods to Avoid: 

Ask your doctor or pharmacist before using any other medicine, including over-the-counter medicines, vitamins, and herbal products. 

• Make sure your doctor knows if you are taking a diuretic (water pills), digoxin (Lanoxin®), a corticosteroid (such as prednisone or cortisone), other antifungal medicine (such as Ancobon®, Nizoral®, or Monistat®) or any antibiotic before you take this medicine. 

Warnings While Using This Medicine: 

• If you are pregnant or breastfeeding, talk to your doctor before taking this medicine. 
• Make sure your doctor knows if you have kidney disease. 

Possible Side Effects While Using This Medicine: 

Call your doctor right away if you notice any of these side effects: 

• Severe nausea and vomiting 
• Shaking and chills 
• Numbness or tingling in the hands or feet 
• Swelling of the face, lips, or tongue 
• Trouble breathing 
• Swelling, pain, or redness near where the IV needle is given 
• Water retention (swelling of the ankles and feet) 
• Urinating less than 1 cup in a day 
• Severe weakness, muscle cramps 

If you notice these less serious side effects, talk with your doctor: 

• Mild diarrhea 
• Mild nausea or upset stomach