Side effects

Amphotericin B may cause side effects. Some side effects are more severe and more common with the first few doses of amphotericin B. Your health care provider may prescribe other medications to decrease these side effects, or tell you to administer amphotericin B every other day. If you have never experienced any of the following side effects from previous doses and suddenly have symptoms, stop your infusion and call your health care provider immediately.

• fever
• chills
• fast breathing
• headache
• changes in heart beat
• dizziness
• fainting
• blurred vision
• nausea
• vomiting
• loss of appetite

Tell your health care provider if any of these symptoms are severe or do not go away:

• pale skin
• flushing
• tiredness
• diarrhea
• stomach cramping
• heartburn
• muscle or joint pain
• weight loss
• ringing in the ears
• hearing loss
• pain, burning, numbness, or tingling in the hands or feet

If you experience any of the following symptoms, call your health care provider immediately:

• rash
• itching
• hives
• difficulty breathing or swallowing
• wheezing
• confusion
• loss of responsiveness or consciousness
• seizures
• decreased urination
• change in heartbeat
• pain in the upper right part of the stomach
• extreme tiredness
• unusual bleeding or bruising
• black and tarry stools
• red blood in stools
• bloody vomit
• vomiting material that looks like coffee grounds
• lack of energy
• yellowing of the skin or eyes
• changes in vision
• flu-like symptoms
• sore throat, chills, cough, and other signs of infection

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online at http://www.fda.gov/MedWatch/report.htm or by phone 1-800-332-1088.