Amprenavir

What  is this medicine? 

AMPRENAVIR (am PREN a veer) is an antiretroviral drug. It  is used with other medicines  to treat HIV. This medicine is not  a cure for HIV. It will not stop  the spread of HIV to others. 

NOTE: This drug is discontinued  in the United States. Patients taking Amprenavir should contact their prescriber regarding discontinuation andalternative therapies. 

This medicine may be used for other purposes; ask your health care provider  or pharmacist if you have questions. 

What  should I tell my health care provider before I take  this medicine? 

They need to know if you have any of these conditions: 

• hemophilia
• if you are of Asian, Eskimo, or Native American descent 
• if you frequently drink alcohol containing drinks 
• kidney disease 
• liver disease 
• an unusual or allergic reaction  to amprenavir, fosamprenavir, sulfa drugs, other medicines, foods, dyes,  or preservatives 
• pregnant  or trying to get pregnant 
• breast-feeding 

How  should I use this medicine? 

Take this medicine by mouth with a glass of water.  Follow the directions on the prescription label. Use a specially marked spoon or container to measure each dose. Ask your pharmacist if  you do not have one. Household spoons are  not accurate. You can  take this medicine with  or without food, but do not  take it with a high fat meal. Take your medicine at regular intervals. Do not take your medicine  more often than directed. For your anti-HIV therapy  to work as well as possible,  take each dose exactly as prescribed. Do not skip doses or stop your medicine  even if you feel better. Skipping doses may make the HIV virus resistant to this medicine and other medicines.  Do not stop taking except on your doctor's advice. 

Talk  to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 4 years for selected conditions, precautions do apply. 

Overdosage: If you think you have taken too much of  this medicine contact a poison control center or emergency room at once. 

NOTE: This medicine is only for you. Do not share this medicine with others. 

What if I miss a dose? 

If you miss a dose by more than 4 hours, wait and take the next dose  at the regular time. But, if you miss a dose by less than 4 hours, take your missed dose right away. Then take your next dose at the regular time. Do not take double or extra doses. 

What may interact with this medicine? 

Do not take this medicine with any  of the following medications: 

• alcohol or any product that contains alcohol 
• astemizole
• bepridil
• cisapride
• disulfiram
• dofetilide 
• flecainide 
• female hormones, like estrogens or progestins and birth  control pills, patches, rings,  or injections 
• medicines for headaches like dihydroergotamine, ergonovine, ergotamine, methylergonovine 
• medicines for cholesterol like atorvastatin, cerivastatin, lovastatin, simvastatin 
• metronidazole 
• midazolam
• pimozide
• propafenone
• ranolazine
• red yeast rice 
• rifampin
• rifapentine 
• ritonavir oral solution 
• triazolam
• St. John's wort 
• vitamin E supplements 

This medicine may also interact  with the following medications: 

• amiodarone
• antacids 
• cyclosporine
• dexamethasone
• fluticasone 
• lidocaine
• medicines for depression, anxiety, or psychotic disturbances 
• medicines for fungal infections like ketoconazole and itraconazole 
• medicines for blood pressure like amlodipine, diltiazem, verapamil 
• medicines for seizures 
• methadone
• other medicines for HIV 
• quinidine
• rapamycin
• rifabutin
• sildenafil
• sirolimus
• tacrolimus
• warfarin

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.