What side effects can this medication cause?

Anagrelide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• headache
• gas
• upset stomach
• vomiting
• diarrhea
• constipation
• stomach pain
• heartburn
• belching
• loss of appetite
• runny nose
• nosebleed
• sore throat
• mouth sores
• dizziness
• depression
• nervousness
• forgetfulness
• confusion
• difficulty falling asleep or staying asleep
• lack of energy or sleepiness
• weakness
• muscle, joint or back pain
• leg cramps
• hair loss
• fever
• flu-like symptoms
• painful urination
• ringing in the ears
• itching

If you experience any of the following symptoms, call your doctor immediately:

• rash
• hives
• unusual bleeding or bruising
• blood in urine or stool
• black or tarry stools
• chest pain
• fluttering sensation in the chest
• fast, forceful, or irregular heartbeats
• swelling of the arms, hands, feet, ankles or lower legs
• difficulty breathing
• cough
• slow or difficult speech
• fainting
• weakness or numbness of an arm or leg
• pain, burning,or tingling in the hands or feet
• seizure
• changes in vision

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online at http://www.fda.gov/MedWatch/report.htm or by phone 1-800-332-1088.