Blood  Coagulation Disorders See Bleeding Disorders; Hemophilia Diagnosis 

Several blood tests can be used to detect various  coagulation disorders. There are hundreds  of different tests  a doctor can order  to look for indications  of specific diseases. In addition  to blood tests, physicians will complete  a medical history  and physical examination. In  the case of acquired coagulation disorders, information  such as prior or current diseases and medications will  be important in determining  the cause of the  blood disorder.

• Hemohilia A will be diagnosed with laboratory tests detecting presence of clotting factor VIII, factor IX,  and others,  as well as  the presence  or absence  of clotting factor inhibitors. 
• Christmas disease will  be checked against normal  bleeding and clotting time, as well  as for abnormal serum reagents in factor IX deficiency. Other tests of prothrombin time and thromboplastic generation  may also be ordered. 
• There is no one test  or group  of tests that can always make (or exclude)  a diagnosis  of DIC. DIC can be diagnosed through  a number  of laboratory tests which measure concentration of platelets  and fibrinogen in  the blood with normal counts and prolonged prothrombin time. Other supportive data include diminished levels  of factors V, fibrinogen,  and VIII, decreased hemoglobin, and others. Since many of the test results also indicate other disorders,  the physician  may have to put together several results  to reach a diagnosis  of DIC. Serial tests  may also be recommended, because a single examine at one moment in time  may not reveal the process that  is occurring. 
• Tests  for thrombocytopenia include  coagulation tests revealing  a decreased platelet count,  prolonged bleeding time,  and other measurements.  If these tests indicate  that platelet destruction is causing  the disorder,  the physician  may order bone marrow examination. 
• Von Willebrand's disease  will be diagnosed  with the assistance  of laboratory tests which show prolonged bleeding time, absent  or reduced levels of  factor VIII, normal platelet count,  and others. 
• Hypothrombinemia is diagnosed  with history information and  the use  of tests  that measure vitamin K deficiency, deficiency of prothrombin,  and clotting factors V, VII, IX, and X. 
• Factor XI deficiency  is diagnosed most  often after injury-related bleeding. Blood tests can help pinpoint factor VII deficiency.