About high cholesterol
About two in three adults have a cholesterol level that is higher than recommended. Having high cholesterol affects your heart and blood vessels and increases your risk of developing cardiovascular disease (CVD). High cholesterol causes fatty deposits (known as plaques) to build up inside your blood vessels.
In time, the blood vessels supplying your heart may become so narrow that they can't deliver enough oxygen to the heart muscle, particularly when you're exerting yourself. This can cause you to feel chest pain (angina). If a fatty plaque breaks off, it may cause a blood clot which can block blood flow to your heart (heart attack) or brain (stroke).
Types of cholesterol
Cholesterol is transported around your body attached to a protein in your blood. This combination of fat and protein is called a lipoprotein. There are different types of lipoprotein, depending on how much fat there is in relation to protein.
HDL (high-density lipoprotein)
A small amount of cholesterol is transported as HDL, which is mostly protein and not much fat. The role of HDL is to transport excess cholesterol from the tissues (including the walls of arteries) to the liver for disposal. As HDL helps prevent cholesterol building up in your blood vessels, you have a decreased risk of heart disease if you have high levels of this type. HDL is considered to be the "good" type of cholesterol. Women tend to have higher HDL levels than men. HDL can be increased by physical exercise.
LDL (low-density lipoprotein)
Most of your body's cholesterol (around 70 percent) is transported in this form. It consists mainly of fat, with not much protein. LDLs are chiefly involved in transporting cholesterol from the liver to the cells. High levels of LDL are associated with an increased risk of CVD as LDL causes cholesterol to be deposited in your blood vessels. LDL is considered to be the "bad" type of cholesterol.
VLDL (very low-density lipoprotein) and chylomicrons
These lipoproteins account for a small percentage of your body's cholesterol, but they are rich in triglycerides and transport them to the tissues.
Triglycerides
Triglycerides are a different type of fat, mostly coming from fats in your food. Energy from food that is eaten and not used immediately is converted into triglycerides and transported to fat cells for storage. This provides you with an important source of stored energy.
Although most triglycerides are stored as fat, low levels are also found in your blood. A raised level of blood triglycerides together with high LDL can increase your risk of heart disease, particularly if you have diabetes.
Total cholesterol (TC)
Having a high TC level is a risk factor for future health problems. However, it's important to consider the relative amounts of HDL and LDL. This is often referred to as the TC:HDL ratio. You should aim for a high level of HDL and a low level of LDL (a low TC:HDL ratio).
Notes:
Dr. M. Kristine Schlossberg
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(last edited February 21, 2010)
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