The definition of kidney.

　　Kidney is a disposer relevant to blood of the body, and has the function of keeping the normal circulation of the human body.

 The treatment method of kidney disease .

　　During the course of occurrence and development of kidney disease, there are six main disease feature:

　　1. Due to impeded blood flow in different levels renal arteries, there will be renal ischemia and anoxia in addition to systematic ischemia and anoxia in every artery system.

　　2. Inflammatory response in all kinds of kidney inherent cells.

　　3. Platelet aggregation and thrombopoiesis in renal blood will lead to the decline of blood flow performance in all the circulatory systems of the body.

　　4. Increase of blood viscosity caused by blood phospholipids variation.

　　5. Because of the damage to the normal structure and function of the kidney, a lot of water and toxins in the blood can not be discharged by the kidney, so they are detained in the tissues and organs in the human body, thus leading to various complications.

　　6. Intrusion of various harmful material and stimulation of various stimulating factors will lead to fibrosis proliferation, also called infinite hyperplasia of extracellular matrix of kidney inherent cells that is renal fibrosis. The six main pathological changes are six main features of kidney disease and the treatment in medical field are based on the six main features.

　　According to the six main disease features above, a lot of treatment experience has been accumulated in medical field and some nichetargeting medicine has been made.

　　① Aiming at artery ischemia and anoxia, vasodilator and hypotensor medicines were created in western medicine including adrenoceptor blocking drug, sympathetic nerve depressant, angiotensin-converting enzyme inhibitor, Calcium antagonists, vascular smooth muscle relaxation medicine etc. ② On account of overreaction of immune inflammation of the patients, hormone and various immune-suppressing drugs were created in western medicine, such as prednisolone, cyclophosphamide, ciclosporin etc. ③ On account of platelet aggregation and thrombopoiesis, heparin and urokinase etc. were created in western medicine, which effectively solved the stagnation of blood flow. ④ Directing at blood viscosity, cholesterol-lowering medicine were made in western medicine which played an effective role in lowering blood fat and improving blood circulation. ⑤ Because the excessive water and various toxins in the blood cannot be discharged by the kidney, western doctors invented substitution therapy, that is artificial kidney. This kind of blood purification and fluid discharging technology has effectively improve the quality of life of the patient and prolonged the life of the patient. However, western medical science cannot solve the hyperplasia of extracellular matrix of kidney inherent cells. That is to say there is no way to block and degrade renal fibrosis.

　　In treating kidney disease, Chinese medicine has created a lot of medicines and methods including discutient, protein-removing medicine, antidinic, anti-vomiting medicine, treating uremia medicine and so on. In treatment methods, we have created many effective methods such as clearing heat and detoxicating, tonifying qi and yin, nourishing yin and the kidney and so on. Especially the method of promoting blood circulation and removing blood stasis which has different effect in every stage of the kidney disease. Clinical practice proves that compound drugs of Chinese medicine can achieve various therapeutic effect by one kind of prescription. If we compare Chinese medical treatment to western medical treatment, we will see that one kind of Chinese compound can achieve the effect of many kinds of western medicine. Take the medicines of activating blood and removing stasis for an example: ① Any medicine of activating blood and removing stasis has the function of dilating blood vessel, and quickly ease the state of ischemia and anoxia; ② Any medicine of activating blood and removing stasis has the effect of anti inflammation and can remove immune inflammation; ③ Any medicine of activating blood and removing stasis has the function of remove thrombopoiesis and platelet aggregation; ④ Any medicine of activating blood and removing stasis has lipid-lowering function that removes blood viscosity; ⑤ Medicine of activating blood and removing stasis has another therapeutic effect which western medicine doesn’t have, that is the unique function of degrading fibrosis hyperplasia, and this has also been approved in clinical practice. Compared with western medicine, the only disadvantage of Chinese medicine is that we haven’t invented the equipment of dialysis and blood purification in renal replacement therapy.

　　It is easy to see from Chinese and western medicine that there are nothing more than six conventional treatments in treating kidney disease: Dilating blood vessel to remit renal ischemia and anoxia; Restrain immune inflammation of the kidney; Anti platelet aggregation and phlebothrombosis; Anti blood viscosity and reduce blood fat inroad; Prevent the forming of fibrosis hyperplasia and renal damage; Remove the toxins and fluid in the body and get rid of complications of Kidney Failure.

　　The characteristics of the treatment in Shijiazhuang Kidney Disease Hospital

　　After years of research, Shijiazhuang Kidney Disease Hospital has founded a special set of four technologies, which includes three characteristic core techniques and one safeguards technique.

　　The three characteristic core technologies refer to the following:

　　(1)Micro-Chinese Medicine Osmotherapy

　　Micro-Chinese Medicine Osmotherapy is an innovative therapy that is summarized by Shijiazhuang Kidney Disease Hospital for many years’ practice. Its core technique is to smash the medicines that are effective to treat kidney disease into amicrons. The purpose is to fully release and mingle the effective ingredients of the medicines. Then, by the penetrating agent and equipment, in the way of external application, the effective ingredients can infiltrate to the kidney nidus, so as to achieve the purpose of curing the kidney diseases. This innovative therapy not only eliminates the side effects of the oral medicine, but also can make the effective ingredients get to the kidney nidus. What’s more, it has been proved in the clinic practice that this is an effective and convenient method. Micro-Chinese Medicine Osmotherapy is now a big characteristic and core supporting technique, which plays a pivotal role in all the treatments. The treating mechanism is as follows: Through the way of vasodilator, anti inflammation, anticoagulationb, anti blood viscidity, and degradating the fibrosis material etc to realize the purpose of blocking the development of the kidney fibrosis, repairing the damaged inherent cells and kidney function, and rebuilding the due kidney structure. It is called blocking, repairing and rebuilding, for short.

　　(2)Stem cell transplant technical system of treatment

　　Stem cell transplant composes the second characteristic core supporting treatment technique. It is introduced as a brand-new method to treat kidney disease and has already showed a strong vitality. Because stem cells have tenacious ability of self-renewal and multi-differentiation, there are infinite possibilities in treating kidney diseases and a strong vitality in repairing and regenerating various kidney inherent cells. So it is called as repairing and rebuilding for short. The adoption of this treating technique greatly increases the treating effect of the kidney diseases.

　　(3)Blood Purification Technology with Immunoadsorbent therapy

　　Blood Purification Technology is third characteristic core supporting treatment technique. The key function of this method is to create a favorable treating environment for the Micro-Chinese Medicine Osmotherapy and stem cell transplant. The treating mechanism is as follows: Eliminate the micromolecular toxin substances by the way of hemodialysis; Eliminate the middle and macro molecular substances through hemofiltration and hemoperfusion; And eliminate immune complex through blood immune adsorbent. And finally effectively sustain the relatively cleaning of the blood so as to have a much more effective effect for stem cell transplant and Micro-Chinese Medicine Osmotherapy. So this method is also called adsorbent and purified.

　　From the introduction of the three characteristic core supporting techniques we can see that Shijiazhuang Kidney Disease Hospital has used them as particular technologies in treating kidney diseases, which has formed her own feature. The combination of these three characteristic techniques highlights the five functions of treating kidney disease, that is blocking, adsorption,purification, repairing and rebuilding. These five functions will have a epoch-making influence in the area of treating kidney diseases.

　　The one guard refers to the safeguards technique of the present treatment. When the hospital establishes the three characteristic core supporting techniques, she also have the current Chinese medical & Medicine, western medical & Medicine as the guard, thereby putting them in the position of safeguard and subordinate. The four techniques form an inalienable organic treatment system.

　　VII Three Insurmountable Courses of Kidney Disease Treatment

　　i. Promoting Blood Circulation, Removing Obstructions & Dilating Artery, Improving Microcirculation (activating metabolic functions of damaged kidney inherent cells)

　　1. Treatment principles of this course.

　　1) Dilating Renal Artery and Digestive Tract Artery, increasing blood perfusion flow of kidney and body.

　　2) Improving and removing the obstructions of partial Microcirculation, increase oxygen supplying and strengthening Metabolism.

　　3) Relieving internal environment disturbance caused by oxygen-deficit.

　　4) Relieving poisoning symptom.

　　2. The usual clinical manifestations appeared after this therapeutic process.

　　1) Once the kidney artery dilated, in virtue of the increasing of effective perfusion flow of kidney glomerulus, the internal pressure and high filtration decrease correspondingly.

　　These necessarily slow down and control the proceeding of glomerulosclerosis. The clinical manifestations appeared as follows.

　　① The urine volume is increasing. The color of urine is darkening and the smell is becoming stronger.

　　② Urine creatinine is increasing gradually. Kidney begins to clear away toxin.

　　③ Urine protein is leaking. Occult blood is disappearing gradually.

　　④ Edema is regressing gradually.

　　2) After the body peripheral artery dilated, the effective blood volume circulation of body is increasing. The Microcirculation Disturbance of skin is improving certainly. The poisoning symptom caused by Renal Failure is relieving. The clinical manifestations appeared as follows.

　　① The languid symptom is relieving gradually.

　　② The skin of face and palm is sanguine.

　　③ The patient begins to sweat.

　　④ The symptom of skin itch is relieving.

　　⑤ The hypertensive symptom is steadying gradually, it is possible to go down to normal. The hypotensor consistent used could be decreased. Some patients could stop taking hypotensor without rebounding.

　　3) The dilation of artery in enteron increases the blood perfusion flow volume of enteron, improves the enteron Microcirculation caused by Renal Failure. The mucous edema of enteron begins to fade away. The secreting of digestive juice is increasing. The function to excrete toxin of intestinal canal is recovering. The clinical manifestations appeared as follows.

　　① The ammoniacal odor inside the oral cavity is disappearing.

　　② The appetite is increasing.

　　③ Uremic Gastritis is relieving. Symptoms of nausea and sick are disappearing.

　　④ The digestive tract function is improving. The function of excreting toxin of intestinal canal is increasing. The bowel is keeping open.

　　ii. The course of Blood Stasis Removal and Clearing Away (degradation and apoptosis of Fiber Cells)

　　1. Treatment principles of this course.

　　1) Chinese Medicine active substance targets at damaged Renal Fibrosis Tissue, MFB and Immune Complex.

　　2) Integrated with Focus Fibrosis Tissue, MFB and Immune Complex.

　　3) Releasing a series of effective pharmaceutical ingredients after integration, launching attack upon Focus Fibrosis Tissue and Immune Complex, leading to the breaking of Fibrosis Tissue and MFB, the breaking parts could be eliminated from the body after the phagocytic cells are activated.

　　4) Active substance of Chinese Medicine could also activate a series of Digestive Enzyme, degrading the Extracellular Matrix and Immune Complex, blocking the worsening chain of Fibrosis.

　　2. The clinical manifestations after this therapeutic process are visible.

　　1) The clinical symptoms are turning better gradually, the patient’s condition is stable basically. Under such condition, the illness condition would not recur if exclude the interruption from infectious elements.

　　2) Urine Examination. Urine is turbid and appearing floccules. Urien Protein and BLD are decreasing gradually. Urine Protein Quantitation is decreasing gradually within 24 hours.

　　3) The state of Blood Electrolyte, Blood Biochemistry and Disorder trend to be balanced.

　　4) Blood Creatinine, Urea Nitrogen and Uric Acid will decrease gradually.

　　5. The filtration rate of Glomerulus is increasing gradually.

　　6. Hemoglobin begin increasing, the anaemic phenomenon is reliving.

　　iii. The Course of Repairing, Rebuilding and Regenerating

　　1. Treatment principles of this course.

　　1) Activating the metabolic function of damaged kidney cells.

　　2). Improving the Renal Failure patient’s condition of Internal Environment Disturbance and oxygen poor. Creating a favorable environment for the repairing.

　　3). Offering essential substance for kidney’s repairing include Vitamin, Trace Elements, Amino Acid and Protein.

　　4). Repairing the organization of Glomerulus Mechanical Barrier and Electrostatic Barrier, recovering the selective filtration function of Glomerulus.

　　2. Clinical Manifestations appeared after this course.

　　1) Clinical symptoms disappear completely.

　　2) Each item of examination index normalizes.

　　3) Anemia is cured. The damages of Viscera Function are full recovery. 

Notes: Kidney Disease And The Treatment Method 　　I. The definition of kidney. 　　Kidney is a disposer relevant to blood of the body, and has the function of keeping the normal circulation of the human body. 　　II.

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