Why is this medication prescribed?  

Cinacalcet is used alone or with other medications to treat secondary hyperparathyroidism a condition in which the body produces too much parathyroid hormone (a natural substance needed to control the amount of calcium in the blood) which can cause serious problems with the bones, heart, blood vessels, and lungs in patients with chronic kidney disease (condition in which the kidneys stop working slowly and gradually) who are being treated with dialysis (medical treatment to clean the blood when the kidneys are not working properly). Cinacalcet is also used to treat high levels of calcium in the blood of patients who have parathyroid cancer (cancer of the glands in the neck that make parathyroid hormone). Cinacalcet is in a class of medications called calcimimetics. It works by signaling the body to produce less parathyroid hormone in order to decrease the amount of calcium in the blood.

How should this medicine be used?  

Cinacalcet comes as a tablet to take by mouth. It is usually taken once a day with food or shortly after a meal. To help you remember to take cinacalcet, take it at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take cinacalcet exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Swallow the tablets whole; do not split, chew, or crush them.

Your doctor will probably start you on a low dose of cinacalcet and gradually increase your dose, not more than once every 2-4 weeks.

Cinacalcet may help control your condition but will not cure it. Continue to take cinacalcet even if you feel well. Do not stop taking cinacalcet without talking to your doctor.

Other uses for this medicine   

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What storage conditions are needed for this medicine?  

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose   

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

• burning, tingling, or unusual feelings of the lips, tongue, fingers, or feet
• muscle aches or cramps
• sudden tightening of the muscles in the hands, feet, face, or throat
• seizures

What other information should I know?     

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your body's response to cinacalcet.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

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