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 Evening Primrose Oil Side Effects
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F.C. Binder
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Evening Primrose Oil 

Introduction 

This fact sheet provides basic information about evening primrose oil—common names, uses, potential side effects, and resources for more information.  Evening primrose is a plant native  to North America, but it grows in Europe and parts of  the Southern Hemisphere as well. It  has yellow flowers that bloom  in the evening. Evening primrose oil contains  gamma-linolenic acid (GLA), an  essential fatty acid. Essential  fatty acids  are required  by the body for growth  and development, and must  be obtained from the diet.
Common Names—evening
  primrose oil, EPO 

Latin Name—Oenothera biennis 

What Evening Primrose Oil Is Used For 

  • Evening primrose oil has been used since the 1930s  for eczema (a condition  in which  the skin becomes inflamed, itchy, or scaly because  of allergies  or other irritation). 
  • More recently it  has been used for other conditions involving inflammation, such as rheumatoid arthritis. 
  • Evening  primrose oil is used for conditions affecting women's health, such as  breast pain associated with  the menstrual cycle, menopausal symptoms, and premenstrual syndrome. 
  • Other conditions  for which evening  primrose oil is used include cancer and diabetes. 
How Evening Primrose Oil Is Used 

Evening  primrose oil is extracted from the seeds  of the evening primrose. The  oil is usually put into capsules for use. 

What the Science Says 
  • Evening  primrose oil may have modest benefits for eczema, and it  may be useful  for rheumatoid  arthritis and breast pain.  However, study results are mixed, and most studies have been small and not well designed. 
  • Evening  primrose oil does not appear to affect menopausal symptoms.
  • Although some clinical trials have shown  a benefit of evening primrose oil for premenstrual syndrome,  the best-designed trials found no effect.
  • There is not enough evidence to  support the use of evening primrose oil for other health conditions. 
  • Side Effects  and Cautions 
  • Evening primrose oil is well tolerated by most people. Mild side effects include gastrointestinal upset  and headache. 
  • Tell your health care providers about any complementary and alternative practices you use. Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe health care. 

Notes:
FCbinderMD
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EditText of this page (last edited April 21, 2010)

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