Fifth Disease Symptoms and Signs:

When a person becomes infected with the virus that causes fifth disease, the virus begins to multiply within the body. Typically, after 4 to 14 days, fifth disease symptoms can begin; however, it may take as long as 20 days for symptoms to appear. The period between becoming infected and the start of symptoms is called the incubation period.
 
Early Symptoms of Fifth Disease:
A few days before the characteristic rash associated with the illness appears, some people may have early signs and symptoms of fifth disease that include:
 

• Low-grade fever
• Body aches
• Tiredness
• Headache
• Chills
• Cold-like symptoms.

Common Fifth Disease Symptoms:

Common fifth disease symptoms are usually mild and can include:
 

• "Slapped cheek" rash on the face
• Lacy, red rash on the trunk, arms, hands, and legs.

Occasionally, the rash may itch. It typically goes away in 7 to 10 days, but can return off and on for several weeks, especially after:
 

• Stress
• Exercise
• Bathing
• Change in temperature
• Exposure to sunlight.