What is flurbiprofen? 

Flurbiprofen is in a group of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs). Flurbiprofen works by reducing hormones that cause inflammation and pain in the body. 

Flurbiprofen is used to treat pain or inflammation caused by arthritis. 

Flurbiprofen may also be used for other purposes not listed in this medication guide. 

What is the most important information I should know about flurbiprofen? 

This medicine may cause life-threatening heart or circulation problems  such as heart attack or stroke. Do  not use flurbiprofen just before  or after having  heart bypass surgery (also called coronary artery bypass graft,  or CABG). 

Get emergency medical help if you have  chest pain, weakness, shortness of breath, slurred speech,  or problems with vision  or balance. 

This medicine  may also cause serious effects on  the stomach or intestines, including bleeding or perforation (forming of a hole).  These conditions can be fatal and can occur  without warning while you are taking flurbiprofen, especially in older adults. 

Call  your doctor at once  if you have symptoms of stomach bleeding  such as black, bloody,  or tarry stools,  or coughing up blood  or vomit  that looks like coffee grounds. 

What should I discuss with my healthcare provider before taking flurbiprofen? 

This medicine may cause life-threatening heart  or circulation problems such as heart attack  or stroke, especially  if you use it long term. Do  not use  flurbiprofen just before  or after heart bypass surgery (coronary artery bypass graft,  or CABG). 

This  medicine may  also cause serious effects on  the stomach  or intestines, including bleeding or perforation (forming of a hole). These  conditions can be fatal and can occur without warning while you  are taking flurbiprofen, especially in older adults. 

Do not use  this medication if you are allergic to flurbiprofen, or if you have: 

• severe kidney disease; or
• a history  of allergic reaction to aspirin  or other NSAIDs. 

• a history  of heart attack, stroke, or blood clot; 
• heart disease, congestive heart failure, high blood pressure; 
• a history of  stomach ulcer or bleeding;
• liver  or kidney disease;
• asthma;
• polyps in your nose; 
• a bleeding  or blood clotting disorder; or
• if you smoke.