Frovatriptan 

Why is Frovatriptan succinate prescribed?

Frova  is used to relieve attacks  of migraine headache. It's helpful whether or not the headache is preceded by an aura (visual disturbances such as seeing halos or flickering lights). 

Experts think  that migraines are caused by the expansion of blood vessels serving the brain,  and that this expansion  is triggered by a decline  in the level of serotonin, one of the brain's chief chemical messengers. Frova works by restoring serotonin levels to normal. It belongs to  a class of drugs called "serotonin agonists." 

Most important fact about  Frovatriptan succinate 

Frova can quell migraine attacks once they've begun, but it won't  prevent them before they start. It should not be used for certain rare types of  migraine called "hemiplegic migraine" or "basilar migraine," and it is not recommended for the "cluster headaches" that tend to affect older men. 

How should you take Frovatriptan succinate?

One Frova  tablet can be  taken any time after  the onset  of a headache.  If the headache goes away and comes back  you can take a second tablet after 2 hours. A third tablet can be taken  2 hours or more  after the last dose.  Do not take more than 3  tablets in one day. 

• If you miss a dose... 
• Frova is not for regular use. Take it only during an attack. 
• Storage instructions... 
• Store Frova tablets at room temperature away from moisture and light. 

What side effects may occur? 

Side effects cannot be anticipated. If  any develop or change in intensity, inform  your doctor as soon as possible. Only your doctor can determine  if it is safe for  you to continue taking Frova 

Side effects may include: 

• Bone pain, dizziness, dry mouth, fatigue, flushing, headache, hot or cold sensation, joint pain, tingling feeling 

Why should Frovatriptan succinate not be prescribed? 

If you have heart disease, you must avoid Frova. You also cannot  take Frovatriptan succinate if you have had  a stroke, suffer mini-strokes,  or have  any other kind of circulation problem. Avoid it, too, if  you have high blood pressure that is  not under control.

Remember that Frova should not be used for "hemiplegic migraine"  or "basilar migraine." Do not use  it again if it causes an allergic reaction, and do not  take it for 24 hours after using another serotonin agonist or an ergot-based migraine medication. Serotonin agonists include almotriptan, naratriptan, rizatriptan, sumatriptan, and zolmitriptan. Ergot medications include such drugs as ergotamine and methylsergide. 

Special warnings about Frovatriptan succinate 

In people with heart disease, medications similar to Frova have been known to cause serious problems, including heart attacks and strokes. If you have heart disease, or know of any factors that make undetected heart disease a possibility, be sure to tell the  doctor. Risk factors include high blood pressure, high cholesterol, diabetes, excess weight, smoking, a history of heart disease in your family, and menopause in women or age over 40 in men. 

If there's any chance of a heart problem,  your doctor may administer the  first dose of Frova in the  office and monitor your response. After later doses, call your doctor immediately if  you develop pain, tightness, heaviness, and pressure in your throat, chest, neck, or jaw. 

Frova is not recommended  for children under age 18. 

Possible food and drug interactions when taking Frovatriptan succinate 

Remember that Frova must never  be combined with other serotonin-agonist  or ergot-based migraine drugs. (See "Why should Frovatriptan succinate not be prescribed?") 

If Frova is taken with certain other drugs,  the effects  of either could be increased, decreased,  or altered. It is especially important  to check with  your doctor before combining Frova with  the following: 

Antidepressants and anti-anxiety drugs that boost serotonin levels, including fluoxetine, fluvoxamine, paroxetine, and sertraline 

Propranolol

Special information if you are pregnant or breastfeeding 

Frova  has not been studied in pregnant women. If you are pregnant  or if you plan to become pregnant, inform your doctor right away so you can discuss your treatment options. 

It  is not known if Frova appears in breast milk. Caution is advised if you plan on nursing. 

Recommended dosage for Frovatriptan succinate 

ADULTS

Take one 2.5 milligram tablet  with a liquid at the onset of headache. If one dose does not work, do not take a second dose, as it is not likely to work either. 

If the headache comes back later, a second tablet can be taken 2 hours or more after the first tablet.  Do not take more than three 2.5 milligram tablets in one day. 

Overdosage

Although little is known about the effects of an overdose of Frova, any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.