How Does Chlorpromazine Work?

Chlorpromazine belongs to a group of medications called typical (or first-generation) antipsychotic medications. In particular, it is part of a group of medications called phenothiazines. It is not entirely known precisely how chlorpromazine works. However, it is known that the drug blocks or lessens the effects of dopamine, a chemical in the brain. Dopamine may be elevated in people with schizophrenia.
 
Chlorpromazine is not a cure for schizophrenia. It only helps to control symptoms.
 
Since dopamine can activate the part of the brain that controls nausea and vomiting, chlorpromazine can treat severe nausea and vomiting by lessening the effects of dopamine in the brain.

When and How to Take Chlorpromazine:

The following are some general considerations for when and how to take chlorpromazine:
 

• Chlorpromazine comes in tablet form. It is usually taken by mouth one to six times daily.
• It does not matter if you take the medication with or without food. If chlorpromazine bothers your stomach, try taking it with food.  
• Chlorpromazine should be taken at the same time(s) each day to maintain even levels of the drug in your blood.
• For chlorpromazine to work properly, it must be taken as prescribed. Chlorpromazine will not work if you stop taking it.

Chlorpromazine Dosage:

The dose of chlorpromazine that your healthcare provider recommends will vary depending on a number of factors, including:

• The medical condition being treated
• Your age and weight
• Other medical conditions you may have
• Other medications you may be currently taking.  

As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.

Notes: eMedTV

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EditText of this page (last edited November 20, 2008)