Why is this medication prescribed?  

Mefloquine is used to treat malaria (a serious infection that is spread by mosquitoes in certain parts of the world and can cause death) and to prevent malaria in travelers who visit areas where malaria is common. Mefloquine is in a class of medications called antimalarials. It works by killing the organisms that cause malaria.

How should this medicine be used?  

Mefloquine comes as a tablet to take by mouth. If you are taking mefloquine to prevent malaria, you will probably take it once a week (on the same day each week). You will begin treatment 1-3 weeks before you travel to an area where malaria is common and should continue treatment for 4 weeks after you return from the area. If you are taking mefloquine to treat malaria, your doctor will tell you exactly how often you should take it. Always take mefloquine with food (preferably your main meal) and at least 8 ounces of water. Children may take smaller but more frequent doses of mefloquine. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take mefloquine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

The tablets may be swallowed whole or crushed and mixed with a liquid such as water, milk, or sugar water.

If you are taking mefloquine to treat malaria, you may vomit soon after you take the medication. If you vomit less than 30 minutes after you take mefloquine, you should take another full dose of mefloquine. If you vomit 30-60 minutes after you take mefloquine, you should take another half dose of mefloquine. If you vomit again after taking the extra dose, call your doctor.

Other uses for this medicine  

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

What storage conditions are needed for this medicine?  

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose  

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Symptoms of overdose may include:

• upset stomach
• vomiting
• diarrhea
• stomach pain
• dizziness
• loss of balance
• headache
• sleepiness
• difficulty falling or staying asleep
• unusual dreams
• tingling in your fingers or toes
• difficulty walking
• seizures
• changes in mental health

What other information should I know?  

Keep all appointments with your doctor and the laboratory. Your doctor may order certain lab tests and periodic eye examinations to check your body's response to mefloquine.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

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