There is no useful screening test and routine pelvic exams rarely find this disease. Most women are diagnosed because they have symptoms.

Unusual bleeding, spotting, or other discharge: If you have gone through menopause, it is especially important to report unusual vaginal bleeding, spotting, or discharge to your doctor.

About 90% of patients diagnosed with endometrial cancer have irregular vaginal bleeding or bleeding after menopause. Although this symptom also can occur with hyperplasia and some other non-cancerous conditions, it is important to have a doctor look into any irregular bleeding right away.

Non-bloody vaginal discharge may also be a sign of endometrial cancer. Even if you cannot see blood in the discharge, that does not mean there is no cancer. In about 10% of cases, the discharge associated with endometrial cancer is not bloody. Any abnormal discharge should be checked out by your doctor.

Pelvic pain and/or mass and weight loss: These symptoms usually occur in later stages of the disease. Nonetheless, delays in seeking medical help may allow the disease to progress even further. This lowers the odds for successful treatment.