What are the symptoms?

The symptoms of Wegener's granulomatosis and their severity vary among patients. General signs of the disease may include:

• Loss of appetite
• Weight loss
• Fever
• Fatigue

Most patients first notice symptoms in the respiratory tract. Symptoms may include:

• Persistent runny nose (also called rhinorrhea) or the formation of nasal crusts and sores
• Nasal or facial pain
• Nose bleeds or unusual nasal discharge, caused by inflammation of the nose or sinuses
• Cough that might include bloody phlegm caused by upper airway or lower airway (lung) inflammation
• Chest discomfort
• Middle ear inflammation (also called otitis media), pain, or hearing loss
• Voice change, wheezing, or shortness of breath caused by inflammation of the trachea

Other possible symptoms include:

• Eye inflammation
• Joint pain (arthritis) or muscle pain
• Rashes or skin sores
• Kidney inflammation*

*Although kidney inflammation is common, it is not usually associated with symptoms, such as pain.