Introduction

This fact sheet provides basic information about bitter orange--common names, uses, potential side effects, and resources for more information. The bitter orange tree is native to eastern Africa and tropical Asia. Today, it is grown throughout the Mediterranean region and elsewhere, including California and Florida. Bitter orange oil is used in foods, cosmetics, and aromatherapy products. Bitter orange oil from the tree's leaves is called petitgrain, and oil from the flowers is called neroli.

Common Names--bitter orange, Seville orange, sour orange, Zhi shi

Latin Names--Citrus aurantium

What It Is Used For

• Bitter orange has been used in traditional Chinese medicine and by indigenous people of the Amazon rain forest for nausea, indigestion, and constipation.
• Current uses of bitter orange are for heartburn, loss of appetite, nasal congestion, and weight loss. It is also applied to the skin for fungal infections such as ringworm and athlete's foot.

How It Is Used

The dried fruit and peel (and sometimes flowers and leaves) are taken by mouth in extracts, tablets, and capsules. Bitter orange oil can be applied to the skin.

What the Science Says

• There is not enough scientific evidence to support the use of bitter orange for health purposes.
• Many herbal weight-loss products now use bitter orange peel in place of ephedra. However, bitter orange contains the chemical synephrine, which is similar to the main chemical in ephedra. The U.S. Food and Drug Administration banned ephedra because it raises blood pressure and is linked to heart attacks and strokes; it is unclear whether bitter orange has similar effects. There is currently little evidence that bitter orange is safer to use than ephedra.